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Systems Biology

Genomic-Epigenomic Engineering

Genomic-Epigenomic Engineering provides the latest technologies for reading, interpreting, and manipulating the genome. Researchers are working to understand how information in the human genome is used by the body. The Human Genome Project has given us the vocabulary of our genes, but epigenetics provides the new frontier of research investigating the layer of regulation of the genome that has profound implications for the treatment of disease and engineering of therapy.

Computational Biology

Computational biologists work at the interface of computer science, sequencing technology, and molecular biology, to address broad questions in personalized medicine, infectious disease, cancer biology, and circulating tumor cells.

Genomic and Epigenomic Engineering

Genomic engineers edit the genome quickly and inexpensively, designing new biological parts. Epigenomic engineers link the environment and genetics, providing a complete understanding of disease risk, early prevention, and intervention.

Data Integration and Modeling

Researchers examine millions of genetic variants and characterize the epigenome, developing new tools for large-scale integrated analysis.

Genomic Assembly

With modern technologies, assembly of new genomes has become practical. Generating a genome for new organisms allows researchers to use molecular tools and to study evolutionary change over time.

Epigenetic Editing

Epigenetic editing is now possible using targeted zinc fingers and modifying the genetic code, chromatin, or DNA methylation marks without changing the sequence per se.

Core Faculty