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Prenatal Diagnosis

Between 5 and 15% of children with Down syndrome in Sweden attend regular school.[108] Some graduate from high school; however, most do not.[17] Of those with intellectual disability in the United States who attended high school about 40% graduated.[109] Many learn to read and write and some are able to do paid work.[17] In adulthood about 20% in the United States do paid work in some capacity.[18][110] In Sweden, however, less than 1% have regular jobs.[108] Many are able to live semi-independently,[12] but they often require help with financial, medical, and legal matters.[9] Those with mosaic Down syndrome usually have better outcomes.[61]

Individuals with Down syndrome have a higher risk of early death than the general population.[20] This is most often from heart problems or infections.[1][8] Following improved medical care, particularly for heart and gastrointestinal problems, the life expectancy has increased.[1] This increase has been from 12 years in 1912,[111] to 25 years in the 1980s,[1] to 50 to 60 years in the developed world in the 2000s.[8][9] Currently between 4 and 12% die in the first year of life.[50] The probability of long-term survival is partly determined by the presence of heart problems. In those with congenital heart problems 60% survive to 10 years and 50% survive to 30 years of age.[12] In those without heart problems 85% survive to 10 years and 80% survive to 30 years of age.[12] About 10% live to 70 years of age.[62] The National Down Syndrome Society provide information regarding raising a child with Down syndrome.[112